Many men ask this question because it influences their success in bed. We can confidently say that one tablet will work at least for 4 hours. This timeframe is indicated in all trustworthy sources that describe the pharmacokinetic properties of the drug.

Can it work longer? – Yes.

The drug may last several hours longer (usually, for 1-2 hours), but it does not work for every man and situation.

How long does Sildenafil take to work? What affects its performance duration? And why are there so many articles on this topic?

These questions bother men no less than the previous one. Let’s figure everything out.

How long does it take for Sildenafil to take effect? We will share information from the manufacturer published in TGA and other sources. It was found that after administration, this medication:

• Works within 30-120 minutes, according to TGA
• It starts to work in 30-60 minutes, according to the data from Viagra’s manufacturer
• Peaks plasma concentrations within 1 hour of administration – PubMed article
• The elimination half-life is 3 to 5 hour – PubMed article

Doctors and drug manufacturers often are careful in their recommendations. The reason is that they have to state clearly the timeline for when the therapeutic effect takes place.

Pharmacological research suggests that:

• Sildenafil’s median time to onset when taken on an empty stomach is 25 minutes (range 12-37 minutes) in 60% of men – according to EMA
• Sildenafil helped 86% of men achieve an erection by 30 minutes after dosing – PubMed article

Strangely enough, many men make the same mistake: they take a pill and wait for its effect. Give Sildenafil time to work. If you don’t know how the medication works for you, you’d better wait for 1 hour.

Strangely enough, many men make the same mistake: they take a pill and wait for its effect. Give Sildenafil time to work. If you don’t know how the medication works for you, you’d better wait for 1 hour.

Sildenafil 100mg How Long Does It Last

The time of action of a drug may depend on the dose. However, the pharmacological response to the changes in concentration of the active ingredient in the blood may be complex and usually non-linear.

Thus, the answer to the question “How long does Sildenafil 100mg take to work?” will be the same as when taking a lower dose. Some men may feel the difference but not each of them.

How Does Sildenafil Work?

Among all the types of ED pills, Sildenafil-containing drugs have the most extended experience of use in men. They are effective in treating any severity and etiology of ED.

So, how Sildenafil citrate works?

It intensifies the natural mechanism of erection. It triggers the relaxation of smooth muscles of three penile arteries, resulting in some biochemical and hemodynamic changes. Blood flows into a spongy body and two cavernous bodies, and a rigid erection occurs.

Does Sildenafil Work in Men Over 65?

The answer will be short – yes. Experimental and clinical research showed that all types of ED pills are effective in men of any age.

Conclusion

We hope you got the answer to the question How long does it take for Sildenafil to work? And will avoid mistakes that many men make.

Follow your doctor’s recommendations, be attentive to how your body responds to the treatment, and you will reduce the risk of failure in bed.