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Viagra Interactions With Other Drugs: What the Studies Say

drugs not to take with Viagra
By 
, reviewed by​
Kim Matthews
 – Updated November 1, 2022
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Viagra (Sildenafil) is a PDE5i, which stimulates circulation, causes erections and improves male sexual performance. Considering that many men treat one or more conditions and take different medicines, it is especially important to be aware of drug interactions.Read our guide on the drugs not to take with Viagra. Learn about the medicines you can take without restrictions and which — with caution.If you do not find the drug in this article or need more information, you can check the interaction with Viagra here: source 1, source 2, source 3.

Ritalin and Viagra

Because Methylphenidate (the active ingredient in Ritalin tablets) is a CNS stimulant, you should not take it with other stimulant drugs or substances.We found no information on the interaction between Viagra and Ritalin or other pharmaceutical products containing Methylphenidate.

Finasteride and Viagra

Doctors can prescribe Finasteride to treat BPH or androgenetic alopecia in men depending on the dosage. The action of this drug is to prevent the conversion of testosterone to dihydrotestosterone.We found information that Sildenafil may reduce the metabolism of Finasteride. Most likely, it will not require dosage changes. No serious interaction was detected.

Tramadol and Viagra

Tramadol-based medicines are centrally-acting opioid analgesics. You should not take them with other analgesics and CNS agents.No significant drug interactions were observed. Taking Tramadol can lead to reduced metabolism of Sildenafil. In other words, Sildenafil will stay and act longer in the body. Most likely, it will not require dosage changes.

Naltrexone and Viagra

Doctors prescribe Naltrexone-containing medicines to treat people with opioid or alcohol addiction. They work in the brain, so you should not take them with sedatives, tranquillizers, CNS depressants, etc.Taking these drugs together is not a contraindication. However, according to eHealthMe and DrugBank, their combination increases the risk of some side effects mainly related to the muscle and skeletal system:
  • Muscle pain;
  • Sprain;
  • Joint injury;
  • Myopathy;
  • Myoglobinuria.

Sertraline and Viagra

Sertraline is a popular SSRI antidepressant. Do not take it, or take it with caution, with most drugs used to treat depressive disorders and other mental illnesses.
  • When you take ED pills, Sertraline may stay in your body longer.
  • When combining these medicines, the dose and time of taking the pills usually do not change.

Statins and Viagra

Statins are lipid-lowering drugs commonly used to lower blood cholesterol and protect the lining of the arteries.You can take the drugs of this group with PDE5is. However, this group has many different medications. And some of them may affect the action of ED pills.

Sotalol and Viagra

Sotalol is a class III antiarrhythmic agent. It prevents irregular heartbeats and makes it easier for the heart to pump blood throughout the body.You should be careful! These drugs have a high potential for interaction. Arterial hypotension is a frequent side effect of Sotalol. Viagra can significantly enhance Sotalol’s hypotensive effect and cause other side effects.

Phentermine and Viagra

Phentermine is an appetite suppressant used in the treatment of overweight or obesity. You should not take medicines of this type with substances that affect the CNS.
  • You can combine Phentermine and Viagra without changing the dosage.
  • Mutual influence of drugs on each other was not found.

Viagra and antibiotics

Doctors prescribe antibiotics, also known as antibacterial agents, to treat infections caused by germs (bacteria and some parasites).There are antibiotics of 5 generations, more than 1000 substances that have an antibacterial effect, and more than 100 antibiotics often used in medicine. Most of them do not affect PDE5 inhibitors, but there are exceptions.Some antibiotics, such as Rifampin (Rifamate, Rifadin, Rimactane) or Erythromycin (Erythroped, Erythrocin, Eryc), have a very strong effect on the metabolism of Sildenafil. Consult a doctor. The doctor will tell you if you can use these pills together or if you should change the dosage.

Twynsta and Viagra

Twynsta is a combination drug that contains 2 active ingredients, Telmisartan and Amlodipine. It is approved for people with high blood pressure. Twynsta relaxes the smooth muscles of the blood vessels, leading to decreased vascular resistance and intra-arterial pressure.Because of the vasodilating effect of Sildenafil, combining these drugs can be dangerous. A doctor will tell you if you can use these medicines together or if you may need to change the dosage.

Paroxetine and Viagra

Paroxetine is a potent antidepressant. You should not take it, or take it with caution, with most medications used to treat depressive disorders or other mental illnesses. Combining Paroxetine and Viagra does not change their pharmacological effect.

Xanax and Viagra

Xanax, as well as other medicines containing Alprazolam, act as CNS depressants. Doctors prescribe them to treat a variety of conditions characterised by anxiety.
  • When you take ED pills, Alprazolam may stay in your body longer.
  • There were found no significant interactions.

Metoprolol and Viagra

Doctors prescribe Metoprolol pills, also known as Betaloc, Lopresor or Minax, to treat hypertension and prevent some cardiovascular diseases. Their therapeutic effect is to reduce the heart rate and relax the walls of blood vessels.Important information! All ED pills have the potential to increase the antihypertensive effect of Metoprolol. A doctor may forbid taking these medicines together or change the dosage.

Citalopram and Viagra

Citalopram (Celapram, Celica, Cipramil, or Talam) belongs to the class of drugs known as SSRI antidepressants. Doctors may prescribe Viagra in combination with Citalopram, including if the use of the antidepressant has caused erection problems.

Pentoxifylline and Viagra

Pentoxifylline is a hemorrheological agent that reduces blood viscosity and improves blood flow through narrowed arteries. This medicine may enhance the antihypertensive effect of PDE5is. A doctor may recommend changing the dosage.

Can you take Panadol with Viagra?

Panadol (Acetaminophen) is an analgesic and antipyretic. Doctors may recommend taking it with Sildenafil, including to relieve headaches caused by ED pills.

Nitroglycerin and Viagra interaction

Important information! Avoid combining these medicines. The risk of the interaction outweighs the benefit. The combination of Nitroglycerin (a vasodilator) and Viagra can cause hypertension, including severe hypertension. The risk of this side effect is very high.

Taking Viagra and Aspirin together

Aspirin is one of the drugs known as NSAIDs. Usually, they use it to relieve mild pain and/or reduce fever. We found no reports of interactions between these drugs.

Isosorbide mononitrate and Viagra

Important information! By no means should you take these medications together. Isosorbide mononitrate and Isosorbide dinitrate belong to the class of nitrates used to treat and/or prevent angina pectoris. Combining these drugs can lead to severe hypertension, circulatory collapse, and other side effects.Viagra and Amyl nitrateImportant information! Do not combine these drugs. When combined with PDE5is, Amyl nitrate, known as poppers, can lower blood pressure and cause severe side effects.

Conclusion

If this article says there is no interaction, it does not necessarily mean there will be no interaction in all cases. We did not describe all possible changes in the effects of Viagra due to recent or concomitant use of other drugs.Do not stop or start taking any medication without first consulting a doctor. Talk to your doctor to ensure you fully understand medications’ risks and benefits.
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