Sildenafil Dosage. Minimum and Maximum Doses

, reviewed by​
Kim Matthews
 – Updated February 2, 2023
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A doctor prescribes the Sildenafil daily dosage taking into account many factors. So, it is different for people with similar age, constitution and other external characteristics.

Sildenafil citrate dosage can range from 5 to 100 mg for a single dose.

The dose of the medicine you take depends on how effective it is for your body.

And the medical problem for which you are using the drug affects:

  • Dosage;
  • Sildenafil dosage timing;
  • Treatment duration.

For erectile dysfunction, if you use the drug orally (tablets):

  • Doctors usually prescribe the Sildenafil dose of 50 mg no more than once a day, one hour before sex, for people under 65 years. However, the timing can range from 30 minutes to 4 hours. If necessary, a doctor adjusts the above dose;
  • For people over 65 years, the standard dose is 25 mg once daily, one hour before sex. The timing can also range from 30 minutes to 4 hours in this case. After evaluating the effectiveness, a doctor can change the dosage;

Children should not use Sildenafil for the above purpose.

For fighting pulmonary arterial hypertension with oral dosage forms (it can be a suspension or tablets):

  • Adults should take from 5 mg to 20 mg three times a day at intervals of 4 to 6 hours.
  • A doctor prescribes individual doses for children.

Usually, doctors don’t prescribe the Sildenafil dosage by weight; the weight doesn’t affect the drug’s action.

Sildenafil tablets 25 mg: best for ‘newcomers’

Doctors often prescribe Sildenafil citrate 25 mg to those who have not used Sildenafil-containing drugs before. This dosage is suitable for most men with a relatively healthy body. Also, it effectively restores erectile function with minimal risk of side effects. Products such as Sildenafil Sandoz 25 mg are excellent for ‘trial runs’. You can test your body for susceptibility to Sildenafil and understand whether such a concentration of the active substance is enough for you to get a full erection.

Sildenafil 50 mg: How to take it safely and with maximum effect?

50 mg of Sildenafil is a standard dose. Usually, men begin the treatment of erectile dysfunction with this dose unless they have any other indications and contraindications.

If Sildenafil 50 mg tablets cause side effects, the doctor reduces the dosage to 25 mg. If they don’t help (or act weakly), the doctor may increase the dose to 100 mg.

Sildenafil 100 mg, how to take

Sildenafil 100 mg dosage is the highest possible dose currently approved in most countries.

It is the most effective dosage. According to a study, Sildenafil 25 mg led to an effective result in 62 % of cases, a dose of 50 mg — in 74 % of cases, and 100 mg — in 82 % of cases (while the volunteers who took a placebo reported an erection in 25 % of cases).

Moreover, when taking a large dose, the time required to achieve an erection decreases and the duration of the drug increases. Two studies gave the following results:

  • In the first study, a 60 % erection (which is enough for sex) occurred on average 25 minutes (in the range of 12-37 minutes) after taking Sildenafil 100 mg and starting stimulation;
  • In the second study, with the RigiScan test, Sildenafil made it possible to achieve a satisfactory erection in response to stimulation 4-5 hours after taking the pill.

However, the higher the dose, the more serious the side effects can be.

How to take Sildenafil citrate 100 mg? Ideally, you should take the drug about 30–60 minutes before sex. You can take Sildenafil before or after meals but keep in mind that fatty foods can reduce the absorption rate of the drug and slow down its action. And if you take a pill on an empty stomach, its action, on the contrary, will accelerate.

Can you take 100 mg of Sildenafil daily? Yes, you can do it. But remember that you should take the drug no more than once a day.

Can I take 150 mg of Sildenafil?

Today, the maximum approved dose of Sildenafil for the treatment of erectile dysfunction is 100 mg once a day. Higher doses are considered off-label use.

It means the drug is not approved for the condition or used at a dose not approved by the TGA.

However, Sildenafil citrate 150 mg red pills are already available. These are extra strong tablets. The manufacturer recommends that you inform your doctor before taking them if you have a history of:

  • Heart attack;
  • Stroke;
  • Heart failure;
  • Heart ischemia and some other diseases.

So far, there is no information on the approval of Sildenafil 150 mg uses by the world’s largest pharmaceutical regulators.

Can I take 200 mg of Sildenafil?

Sildenafil 200 mg is also considered “off-label” use.

For information: In a study, volunteers took (single) doses of Sildenafil up to 800 mg.

The researchers concluded that 200 mg of Sildenafil citrate doesn’t improve the drug’s effectiveness but increases the incidence of adverse reactions. And when taking 800 mg, side effects were the same as at lower doses, but their frequency and severity were much higher.

How much Sildenafil is too much?

Do you want to be sure that the planned sex will happen?

How much Sildenafil should I take in this case?

Those interested in answer to this question should know that the maximum dose of Sildenafil in 24 hours is 100 mg. But it should be a single dose. If you take a 25 mg or 50 mg tablet, you shouldn’t add another 75 mg or 50 mg for at least 24 hours after taking it.

A doctor prescribes the Sildenafil max dose considering your body’s characteristics. The doctor can also increase or decrease the dose during the treatment.

Exceeding (or even increasing) the dose can increase the risk of side effects. They include:

  • Headache;
  • Nausea;
  • Vision impairment;
  • Nasal congestion;
  • Muscle pain;
  • Back pain;
  • Dizziness;
  • Rash.

For example, 16% of people taking Sildenafil 25 mg reported headaches. And 28% of people taking Sildenafil 100 mg reported headaches (Dhaliwal, 2020).


Sildenafil citrate occupies a leading position in the world rankings of drugs for potency treatment. This ED drug demonstrates high effectiveness because, according to statistics, more than 70 % of men have a full erection during the action of Sildenafil.

At the same time, you should remember that ideal drugs don’t exist. The effectiveness of Sildenafil depends on the correctness of the selected dose. Don’t start your acquaintance with Sildenafil with large doses (exceeding 100 mg). Even if you have excellent health and have never experienced heart and lung pathologies and problems with blood vessels, you should start with doses of 25 mg and 50 mg. These doses will help you understand your body’s reaction to the drug and create the proper regimen for further use.

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